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MDMA (3,4-methylenedioxymethamphetamine), commonly known as ecstasy or molly, is a synthetic psychoactive substance that has been widely used in the United States, particularly among adolescents and young adults.

Usage Statistics

• Lifetime Use: As of 2023, approximately 22.3 million Americans aged 12 and older have used MDMA at least once in their lifetime. citeturn0search9
• Past-Year Use: In 2021, about 0.8% of individuals aged 12 or older reported using MDMA in the past 12 months. Among high school students, usage rates were 0.6% for 8th graders, 0.7% for 10th graders, and 1.1% for 12th graders. citeturn0search3
• Young Adults: The highest usage rate is observed among young adults aged 18 to 25, with 7.1% reporting past-year use. citeturn0search6

Health Risks and Overdose

MDMA use is associated with several health risks, including:

• Overdose: MDMA-related emergency department visits have increased over the years, with more than 22,000 visits reported in 2011. citeturn0search1
• Polydrug Use: Users often combine MDMA with other substances like GHB, ketamine, and methamphetamine, which can increase the risk of adverse effects. citeturn0search1
• Adulteration: MDMA is frequently mixed with other drugs, such as bath salts or methamphetamine, which can lead to unpredictable and dangerous effects. citeturn0news12

Therapeutic Research

Despite its classification as a Schedule I controlled substance, MDMA has been studied for its potential therapeutic benefits:

• PTSD Treatment: Clinical trials have shown that MDMA, when used in conjunction with psychotherapy, can significantly reduce symptoms of post-traumatic stress disorder (PTSD). citeturn0news19
• FDA Designation: In 2017, the U.S. Food and Drug Administration granted MDMA “breakthrough therapy” designation for its potential use in treating PTSD. citeturn0search3

Harm Reduction and Education

Given the risks associated with MDMA use, harm reduction strategies are essential:

• Education: Informing users about the potential dangers and the importance of testing substances for purity can help mitigate risks.
• Testing Kits: Organizations promote the use of drug testing kits to identify adulterants and ensure safety.

If you or someone you know is struggling with MDMA use, seeking professional help and utilizing available resources is crucial for health and safety.